Studies on the serum iron-binding capacity

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Studies on the Serum Iron-binding Capacity.

The total iron-binding capacity of serum has been estimated using a colorimetric method, a radioisotopic technique, and a method employing immunodiffusion. The modified isotopic technique described was considered to be the method of choice. The total iron-binding capacity starts to increase at an early stage of an iron-deficiency anaemia. It is decreased in infectious and malignant disease. Clo...

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Determination of the Serum Iron-binding Capacity.

A colorimetric and an isotopic method for determining the iron-binding capacity are described, using only 1 ml. samples of plasma or serum. Both methods are simple, rapid and sensitive. Satisfactory results are obtained from frozen as well as from fresh samples.

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Intravenous iron-dextran: studies on unsaturated iron-binding capacity.

A method is described for measuring the plasma unsaturated iron-binding capacity in the presence of very high concentrations of iron as iron-dextran. The procedure utilizes (59)Fe to label the apotransferrin with subsequent separation of ionic iron from transferrin-bound iron on an ion exchange or Sephadex G.25 column. The unsaturated iron-binding capacity has been measured in rabbits and dogs ...

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Total iron-binding capacity calculated from serum transferrin concentration or serum iron concentration and unsaturated iron-binding capacity.

in borderline cases. The routine use of other biomar-ker assays, such as HFABP in conjunction with tGST activity, could provide complementary information on the potential allograft " viability ". This is illustrated by the fact that there was better segregation of donor categories (controlled vs uncontrolled) with HFABP than with tGST activity. This finding therefore warrants continued evaluati...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1965

ISSN: 0021-9746

DOI: 10.1136/jcp.18.4.446